ABSTRACT
Objective:To put forward suggestions for the problems identified in the application of Artificial Intelligence in the field of medical research management.Methods:Literature review were conducted to analyze the concept of Artificial Intelligence and its application in the field of medical scientific research management. The existing problems of medical Artificial Intelligence projects were identified and feasible countermeasures were put forward.Results:A total number of 16 Artificial Intelligence projects were going in the hospital. Some problems were identified during the management process, which including lack of regulatory regulations and professional standards, the communication barriers between the two partners are also prominent, the collection, sharing, and quality control of medical big data need to be standardized and managed ethically.Conclusions:Taking into account of the problems identified in the management of Artificial Intelligence projects in hospitals, scientific research management should put forward some countermeasures, such as improving management system and supervision mechanism, strengthening top-level guidance and improving employment capacity, paying attention to process management and fine business process, focusing on data supervision to promote business format promotion, cultivating talents to help comprehensive development, strengthening ethical awareness and risk management.
ABSTRACT
Objective:To establish a scientific, directional and operable evaluation index system for clinical disciplines, which can meet the needs of discipline construction and is suitable for the evaluation and selection of various disciplines in oncology hospitals, so as to provide decision-making basis for discipline construction.Methods:Literature analysis and in-depth interview were used to draw up the preliminary evaluation index system. The index frame of subject evaluation was compiled, and the expert inquiry paper was compiled, and the index was added, subtracted and modified by Delphi method through two rounds of expert consultation. The index weight was determined by Analytic hierarchy process. Each index was given a specific scoring standard. The evaluation index system was used to test and analyze 22 clinical medical disciplines in the hospital. The total score of each discipline was calculated by weighted summation method. The validity of evaluation was judged by Spearman grade correlation analysis.Results:The clinical discipline evaluation index system consisted of 4 first-class indexes, 10 second-class indexes and 34 third-class indexes. The weights and scoring criteria of each index were determined. 22 disciplines were evaluated by the index system, which was divided into three grades: excellent, medium and poor.Conclusions:The evaluation index system of clinical discipline constructed in this study has high authoritative coefficient of experts, and the P value is less than 0.01.The evaluation results of 22 disciplines are highly correlated with those of experts, and the P value is less than 0.01. It has strong scientific validity and feasibility, and lays a foundation for the widespread application of clinical evaluation.
ABSTRACT
Objective To investigate the hospital laboratory management mode.Methods We used literature review and comparative analysis to understand the different laboratory management mode,explore suitable operation mechanisms for hospital research and the development of hospital la boratory.Through a variety of measures to improve the efficiency and level of management,we tried to ensure the high efficiency and high quality operation of clinical laboratory,hospital science research,personnel training,discipline construction to provide quality services.Results There were two kinds of hospital laboratory management modes,which were centralized and decentralized management mode.Both management modes had advantages and disadvantages.We thought the centralized-decentralized binding mode was an ideal combination.Based of this mode,we implemented a number of initiatives and achieved significant results.Conclusions From the scale of hospital and its long-term development,centralized decentralized binding mode is a kind of ideal mode.
ABSTRACT
Discipline construction is the core of the construction and development of hospital,the situation of discipline construction reflects the overall strength,academic position and core competitiveness of the hospital.The construction of clinical discipline mainly includes three contents:the construction of academic team,the determination of the subject direction,and the construction of the discipline platform.Scientific research is the main content of discipline construction.High level of research is the carrier of discipline construction.We have performed many management measures:improving the scientific management system,strengthening the dynamic management of the department,global planning,paying attention to personnel training and talent introduction,building reasonable talent echelon and advanced platform to create a good academic environment.According to these measures we have achieved fruitful results.
ABSTRACT
Cultivation of medical scientific research personnel is the driving force and source of the development of medicine.Powerful medical scientific research management would improve the overall level of hospital scientific research.Through the strengthening of discipline construction,the establishment of cooperation and communication platform,the implementation of an effective incentive mechanism,the improvement of research supporting conditions,the improvement of the quality of personnel management,the construction of scientific research management platform,we effectively enhanced the ability of scientific research personnel,and improved the level of scientific research in our hospital.
ABSTRACT
The factor that how the research funding is managed and used is very important for the progress and quality of research projects.With the continuous increase in the degree of supervision for the research fund,the attention to scientific research funding in hospital is also gradually raised.The problems of mismanaged and misuse research fund has been highlighted.The current study,based on the characteristics of medical research,comprehensively analyzed the existing problems of medical research funding in use and management from the point of view of research management.To solve these problems,we proposed suggestions and countermeasures to improve the use and management of research funding,and continued to improve the management of research funding.
ABSTRACT
Research integrity leads the social credit system.for researchers in large hospitals in China,the pressure from clinical work and temptations caused by research outcomes sometimes lead to scientific dishonesty.Strengthening the construction of scientific ethics and maintaining social prestige of science has become an important task for research community in our country.This paper analyzed the causes of scientific dishonesty and explored the ways to improve research integrity in large hospitals,including providing education and training in research ethics,and establishing and strengthening the regulations in research ethics.
ABSTRACT
The quality and quantity of scientific research project are important indexes to evaluate the comprehensive scientific research strength of organizations.To improve the quality of grant and successful of application rate,we applied the circulation to scientific research management.We utilized fishbone analysis method to analyze the factors associated with successful rate of research projects and performed many countermeasures.According to the measurements,the quality of research project,management and successful rate has been continually improved.
ABSTRACT
Through literature review,Delphi method and analytic hierarchy process,the construction and implementation of evaluation system on researchers' performance is in accordance with characteristics and practical requirements of Peking University Cancer Hospital & Institute,19 key indicators,which fall into 3 categories of work aptitude,work behavior,and work effectiveness,were set up as the basic structure,and upon wich the development and implementation of performance evaluation system is based and possible effects and results were discussed.
ABSTRACT
It is getting very competitive in the application to Natural Science Foundation of China.To improve the chances of success in the application, we summarized and analyzed the peer review opinions for the 91 failed applications from 2004 to 2008. Problems were disclosed for these application projects in scientific significance, research content, research design, novelty, preparative research, research group,and application writing. Countermeasures were proposed for the department of research to improve the application quality.
ABSTRACT
Objective To explore the different mechanisms of to cisplatin (CDDP) resistance in human epithelial ovarian cancer cell lines by two different methods. Methods Two resistant cell lines were established: SKOV3/CDDP-P and SKOV3/CDDP-80. They were induced from epithelial ovarian cancer cell line SKOV3 respectively by pulse and intermittent exposures to cisplatin during the period of 16 months. The biological characteristics of all the cell lines were determined using light microscopy and cell counting. Drug sensitivity was monitored by MTT assay. The cell cycle was examined by flow cytometry. The mRNA expression of MDR1,MRP1,LRP1 and GST-? was determined by RT-PCR. Results The resistance indexes of SKOV3/CDDP-P and SKOV3/CDDP-80 were 4.12?2.01 and 11.50?3.15,respectively. Both the two resistant cell lines had some changes in biological characteristics in which SKOV3/CDDP-80 showed more distinct changes. The expression of MDR1 was up-regulated,and the expression of MRP1 and LRP1 was down-regulated,and the expression of GST-? showed no significant changes inSKOV3/CDDP-P. However,SKOV3/CDDP-80 showed a great increases in MDR1,and there was no significant changes in MRP1,LRP1 and GST-?. Conclusion The results suggest that there are many differences between the two resistant cell lines which involved in multi-gene changes. The intermittent administration has greater trend to develop resistance.